Leg Cramps at night.

I got switched up on Meds and now I get leg cramps in my calves almost every night.  They wake me from sleeping and hurt like a bitch.  Has anyone ever had this happen?  It really sux.  the meds are called symbrax.   But, I was getting them before the change to so I'm not sure what the problem is.  I take vitamins, I eat.  All I know is they are so bad it hurts in the daytime after the cramps in the night.  I looked on the web.  Maybe I just need more water.